Khmel’nitskii, Yu. L.; Martinek, K. published the article 《Enzymatic synthesis in biphasic water-organic systems. V. Optimization of preparative synthesis of a peptide》. Keywords: optimization peptide synthesis chymotrypsin catalyst; enzyme peptide synthesis biphasic system.They researched the compound: H-Leu-NH2.HCl( cas:10466-61-2 ).COA of Formula: C6H15ClN2O. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:10466-61-2) here.
α-Chymotrypsin-catalyzed coupling of Ac-Trp-OH with H-Leu-NH2-HCl in EtOAc-H2O were optimized. The product, Ac-Trp-Leu-NH2, was obtained in ∼100% yield under the following conditions: EtOAc/H2O volume ratio 50, aqueous phase pH 6-9, and initial reactant concentrations 3 × 10-9 M.
Here is just a brief introduction to this compound(10466-61-2)COA of Formula: C6H15ClN2O, more information about the compound(H-Leu-NH2.HCl) is in the article, you can click the link below.