1,3-Dimethyl-1H-benzo[d]imidazol-3-ium iodide, cas is 7181-87-5, it is a common heterocyclic compound, the chiral-catalyst compound, its synthesis route is as follows.,7181-87-5
(1) Weigh 0.2 mmol (54.8 mg) of 1,3-dimethylbenzimidazole oxime iodide, 0.1 mmol (40.6 mg) of 1,4-diiodobiphenyl (both feed ratios of 2:1) as a substrate, 2 mg of Group IB copper salt Cu(OAc)2¡¤H2O (10 mol% equivalent relative to 1,4-diiodobiphenyl) as a catalyst, 0.2 mmol (16.4 mg) of sodium acetate as an additive, put the substrate, catalyst, additive and mixing into the reaction kettle, An aprotic solvent N,N-dimethylformamide (1 ml) was added as a reaction solvent, and the mixture was reacted at 100 C for 10 hours. After completion of the reaction, dichloromethane (5 ml) was added, filtered, and then washed twice with water (5 ml) and ethanol (5 ml). The obtained yellow filter residue is a pure product biphenyl bridged bisbenzimidazole, the yield was 90%. The nuclear magnetic resonance spectrum is shown in Figure 2: (deuterated dimethyl sulfoxide as solvent, Bruker AMX-400 nuclear magnetic resonance instrument). 1H NMR (400 MHz, DMSO-d6): delta = 8.28 (d, J = 8.0 Hz, 4H), 8.18 (d, J = 4.8 Hz, 4H), 8.11(d, J = 7.6 Hz, 4H), 7.80 (d, J = 4.8 Hz, 4H), 3.98 (s, 12H).High resolution mass spectrometry (Waters-Q-TOF Premier detector). HRMS (ESI) : C30H28IN4+ ([M-I-]+) calc.: 571.1353, Found: 571.1398.
7181-87-5 is used more and more widely, we look forward to future research findings about 1,3-Dimethyl-1H-benzo[d]imidazol-3-ium iodide
Reference£º
Patent; Guilin University of Technology; Li Shiqing; Li Yongshu; Liang Xiajing; Liu Yunfeng; Chen Ziyuan; Pan Meiling; (6 pag.)CN109734670; (2019); A;,
Chiral Catalysts
Chiral catalysts – SlideShare