141556-45-8, 1,3-Dimesityl-1H-imidazol-3-ium chloride is a chiral-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
8. Chemical reaction involving potassium metal in phosphonium-based ionic liquids: generation of an NHC in a PIL; [00063] l,3-6/s(2,4,6-trimethylphenyl) imidazolium chloride (2.00 g, 5.87mmol) and an excess of potassium metal (0.35 g, 8.75 mmol), previously washedwith anhydrous THF, were added to trihexyl(tetradecyl) phosphonium chloride (10 mL). The reaction mixture was heated at 80 C under nitrogen for 24 hours. Hexanes (10 ml) were added to the resulting suspension and the solution was filtered through Celite to remove undissolved materials. Evacuation to remove hexanes gave a brown viscous residue that was characterized as a solution of trihexyl(tetradecyl) phosphonium chloride and l,3-ft/s(2,4,6-trimethylphenyl)-imidazol-2-ylidene.; 10. Formation of ./V-heterocvclic carbenes in phosphonium-based ionic liquids; [00065] l,3-&w(2,4,6-trimethylphenyl)imidazolium chloride (0.25 g, 100% 13Clabeled at C2) and a solution composed of ether free PhMgBr (2.00 mmol) dissolved in trihexyl(tetradecyl) phosphonium decanoate (5 mL) were mixed at room temperature. A small amount of toluene was added to reduce the viscosity and to facilitate stirring. NMR studies on the reaction mixtures show the presence of a major peak in the 13C NMR spectrum at 218 ppm, consistent with the formation of l,3-Z>/.s(2,4,6-trimethylphenyl) imidazol-2-ylidene.[00066] l,3-*w(2,4,6-trimethylphenyl) imidazolium chloride (2.00 g, 5.87mmol) and an excess of potassium metal (0.35 g, 8.75 mmol), previously washed with anhydrous THF, were added to trihexyl(tetradecyl) phosphonium chloride (15 mL). The reaction mixture was heated at 80 C under nitrogen for 24 hours. Hexanes (10 mL) were added to the resulting suspension and the solution was filtered through Celite. Evacuation to remove hexanes gave a reddish brown viscous material, and this residue was characterized as a solution of trihexyl(tetradecyl) phosphonium chloride and l,3-izs(2,4,6-trimethylphenyl)imidazol-2-ylidene.
As the paragraph descriping shows that 141556-45-8 is playing an increasingly important role.
Reference£º
Patent; SIMON FRASER UNIVERSITY; WO2006/7703; (2006); A1;,
Chiral Catalysts
Chiral catalysts – SlideShare