HPLC of Formula: 22468-26-4. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 4-Hydroxypicolinic acid, is researched, Molecular C6H5NO3, CAS is 22468-26-4, about Microbial degradation of dipicolinic acid by a laboratory isolated strain of Bacillus brevis. Author is Singh, Ravindra Pal.
A B. brevis isolated from soil utilizes dipicolinic acid (I) as a sole C and N source. O2 uptake by the vegetative cells was equivalent to I utilized. L-Ascorbate, however, inhibited both O2 uptake and I utilization. Amino acids served individually as C and N sources, but glycine or glyoxalate not only failed to support growth but inhibited metabolism when added with normal substrates. I catabolites were identified as 4-hydroxy-I and a keto acid. Apparently, the 1st step in I utilization is hydroxylation at position C-4 of the I ring, giving rise to C3 and C4 fragments upon ring cleavage. A possible pathway for I degradation by this organism is proposed.
There is still a lot of research devoted to this compound(SMILES：O=C(O)C1=NC=CC(O)=C1)HPLC of Formula: 22468-26-4, and with the development of science, more effects of this compound(22468-26-4) can be discovered.