22795-99-9, (S)-(1-Ethylpyrrolidin-2-yl)methanamine is a chiral-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: In a clean and dry Tiny-clave reactor covered with aluminum foil, 1-iodo-m-carborane (0.09 mmol), amine (0.135 mmol), base (0.27 mmol) and ligand (4 molpercent with respect to carborane) were solved in degassed dry THF (1 mL). The catalyst (2 molpercent with respect to carborane) was added and the solution was degassed one more time. The reactor was closed and filled with the required pressure of CO, placed in a pre heated oil bath and heated at 85?C. Progress of the reaction was monitored by GC-MS analysis. After finishing the reaction, the oil bath was removed, cooled to room temperature and the CO was flushed with nitrogen. The reaction mixture was filtered through a celite bed. The celite was washed with ethyl acetate and the collected filtrates were concentrated and purified by column chromatography. Conditions were as follows:Compound 1: chloroform/ethanol 75/25; Compound 2: chloroform/ethanol 95/05; Compound 3: chloroform/ethanol 92/08; Compound 4: chloroform/ethanol 92/08, 22795-99-9
As the paragraph descriping shows that 22795-99-9 is playing an increasingly important role.
Reference£º
Article; Gona, Kiran Babu; Go?mez-Vallejo, Vanessa; Llop, Jordi; Tetrahedron Letters; vol. 54; 8; (2013); p. 941 – 944;,
Chiral Catalysts
Chiral catalysts – SlideShare