7181-87-5, 1,3-Dimethyl-1H-benzo[d]imidazol-3-ium iodide is a chiral-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
(1) Weigh 0.2 mmol (54.8 mg) of 1,3-dimethylbenzimidazole oxime iodide, 0.1 mmol (40.6 mg) of 1,4-diiodobiphenyl (both feed ratios of 2:1) as a substrate, 2 mg of Group IB copper salt Cu(OAc)2¡¤H2O (10 mol% equivalent relative to 1,4-diiodobiphenyl) as a catalyst, 0.2 mmol (16.4 mg) of sodium acetate as an additive, put the substrate, catalyst, additive and mixing into the reaction kettle, An aprotic solvent N,N-dimethylformamide (1 ml) was added as a reaction solvent, and the mixture was reacted at 100 C for 10 hours. After completion of the reaction, dichloromethane (5 ml) was added, filtered, and then washed twice with water (5 ml) and ethanol (5 ml). The obtained yellow filter residue is a pure product biphenyl bridged bisbenzimidazole, the yield was 90%. The nuclear magnetic resonance spectrum is shown in Figure 2: (deuterated dimethyl sulfoxide as solvent, Bruker AMX-400 nuclear magnetic resonance instrument). 1H NMR (400 MHz, DMSO-d6): delta = 8.28 (d, J = 8.0 Hz, 4H), 8.18 (d, J = 4.8 Hz, 4H), 8.11(d, J = 7.6 Hz, 4H), 7.80 (d, J = 4.8 Hz, 4H), 3.98 (s, 12H).High resolution mass spectrometry (Waters-Q-TOF Premier detector). HRMS (ESI) : C30H28IN4+ ([M-I-]+) calc.: 571.1353, Found: 571.1398.
As the paragraph descriping shows that 7181-87-5 is playing an increasingly important role.
Reference£º
Patent; Guilin University of Technology; Li Shiqing; Li Yongshu; Liang Xiajing; Liu Yunfeng; Chen Ziyuan; Pan Meiling; (6 pag.)CN109734670; (2019); A;,
Chiral Catalysts
Chiral catalysts – SlideShare