Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 921-60-8, Name is L-Glucose, molecular formula is , belongs to chiral-catalyst compound. In a document, author is Li, Tianlu, Recommanded Product: 921-60-8.
Regioselective protection of the polyfunctional carbohydrates with acyl groups under catalytic conditions is a prerequisite for efficient structural modification and chain extension via glycosidation. A general and also strong axial oxy group effect was now observed with benzoyl cyanide as the acylating agent and 4-dimethylaminopyridine as the catalyst, permitting the preferred O-acylation of equatorial hydroxy groups next to axial oxy groups. This effect is substantiated with 2,3-O-unprotected beta-D-galacto- and alpha-D-glucopyranosides and 3,4-O-unprotected mannopyranosides possessing vicinal trans-diol moieties. Moreover, vicinal trans-diols with axial oxy groups next to each hydroxy group, possessing expectedly comparable reactivity, could be differentiated with chiral tertiary amine catalysts. Particularly interesting in this regard is the action of bifunctional (S,S)-N-(N,N-dialkylaminocyclohexyl)-thioureas as catalysts; they favor 2-O-benzoylation of 2,3-O-unprotected alpha-galactopyranosides, as is also supported by density functional theory calculations. This directing effect can be reversed with quinidine as the catalyst or with bulky substituents at the anomeric position.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 921-60-8, in my other articles. Recommanded Product: 921-60-8.
Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare