Chemistry can be defined as the study of matter and the changes it undergoes. You’ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 541-14-0, Name is (S)-3-Hydroxy-4-(trimethylammonio)butanoate, molecular formula is , belongs to chiral-catalyst compound. In a document, author is Dong, Guizhi, COA of Formula: C7H15NO3.
An unprecedented catalytic asymmetric allylation of isatins and isatin-derived ketimines is reported enabled by a gold and chiral organocatalyst cooperative catalysis strategy. This method offers expeditious access to chiral 2,5-disubsituted alkylideneoxazolines containing vicinal stereogenic centers, mainly in optically pure form, and which are otherwise impossible to access. Mechanistic evidence reveals the presence of an alkylgold intermediate, and an X-ray crystal structure of the allylgold species illuminates its unique stability and reactivity. An asymmetric formal hetero-ene reaction of this gold intermediate, involving a dearomatization process, is enabled with assistance of a quinine-derived squaramide catalyst. This novel discovery extends the synthetic applications of gold complexes and the versatility of gold catalysis.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 541-14-0, in my other articles. COA of Formula: C7H15NO3.
Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare