The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.21436-03-3, Name is (1S,2S)-Cyclohexane-1,2-diamine, molecular formula is C6H14N2. In a Article£¬once mentioned of 21436-03-3, Safety of (1S,2S)-Cyclohexane-1,2-diamine
Concentration Effect in the Asymmetric Michael Addition of Acetone to beta-Nitrostyrenes Catalyzed by Primary Amine Thioureas
Bifunctional primary amine thiourea (PAT) organocatalysts show remarkable improvement in enantioselectivity and catalytic activity (turnover frequency) in the asymmetric Michael addition of acetone to beta-nitrostyrenes upon dilution. Mechanistic investigations indicate that this behavior corresponds to the inhibition of off-cycle catalyst deactivation at low concentration, rather than to the operation of aggregation phenomena at high concentration. Reaction at low concentration (?0.2 M in beta-nitrostyrene) leads to the minimization of catalyst deactivation and, thus, to the optimization of yield and ee of the Michael addition products.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Safety of (1S,2S)-Cyclohexane-1,2-diamine, you can also check out more blogs about21436-03-3
Reference£º
Chiral Catalysts,
Chiral catalysts – SlideShare