Synthetic Route of 21436-03-3, An article , which mentions 21436-03-3, molecular formula is C6H14N2. The compound – (1S,2S)-Cyclohexane-1,2-diamine played an important role in people’s production and life.
Self-assembly of noncyclic bis-D- and L-tripeptides into higher order tubular constructs: Design, synthesis, and X-ray crystal superstructure
(Figure Presented) Trans (1R,2R)-diaminocyclohexane was used as a semirigid vicinal diamine to anchor two N-protected tripeptides consisting of L-D-L amino acids as carboxy terminal amides. The bis-tripeptide consisting of L-Ser (OBn)-D-Ser (OBn)-L-Ser (O-p-bromobenzyl) Boc afforded X-ray quality crystals containing benzene and chloroform solvent molecules. Analysis of the solid-state structure revealed a highly H-bonded helical open-ended tubular superstructure. The tripeptide strands intertwine like a pair of self-embracing arms, held together by a gamma-turn and a 14-membered antiparallel H-bonded macroring spanning the first and third amino acid residues within each strand. Whereas the tripeptide from the R,R anchor gave beautiful crystals from benzene and chloroform, the analogous construct from the S,S-anchored diamine gave a gel. Related bis-tripeptides with different amino acids showed extensive intramolecular H-bonding based on NMR titration and dilution experiments.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 21436-03-3, help many people in the next few years., Synthetic Route of 21436-03-3
Reference£º
Chiral Catalysts,
Chiral catalysts – SlideShare