Recommanded Product: 931-40-8. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: 4-(Hydroxymethyl)-1,3-dioxolan-2-one, is researched, Molecular C4H6O4, CAS is 931-40-8, about Assessing the pKa-Dependent Activity of Hydroxyl Hydrogen Bond Donors in the Organocatalyzed Cycloaddition of Carbon Dioxide to Epoxides: Experimental and Theoretical Study. Author is Yingcharoen, Prapussorn; Kongtes, Chutima; Arayachukiat, Sunatda; Suvarnapunya, Kittipong; Vummaleti, Sai V. C.; Wannakao, Sippakorn; Cavallo, Luigi; Poater, Albert; D’ Elia, Valerio.
The development of hydrogen bond donors (HBDs) as catalytic moieties in the cycloaddition of carbon dioxide to epoxides is an active field of research to access efficient, inexpensive and sustainable metal-free systems for the conversion of carbon dioxide to useful chems. Thus far, no systematic attempt to correlate the activity of a diverse selection of HBDs to their physico-chem. properties has been undertaken. In this work, we investigate factors influencing the catalytic activity of hydroxyl HBDs from different chem. families under ambient conditions by considering the HBDs Bronsted acidity (expressed as pKa), the number of hydroxyls and structural aspects. As an effect, this study highlights the crucial role of the hydroxyl protons’ Bronsted acidity in determining the catalytic activity of the HBDs, identifies an ideal range for the hydroxyl HBDs proton acidity (9