Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 521284-22-0, Name is (R)-2-((4-Aminophenethyl)amino)-1-phenylethanol hydrochloride, molecular formula is C16H21ClN2O, belongs to chiral-catalyst compound, is a common compound. In a patnet, author is Gonzalez-Martinez, Daniel, once mentioned the new application about 521284-22-0, Product Details of 521284-22-0.
A series of amino alcohols have been prepared in a chemo-, diastereo- and enantioselective fashion starting from the corresponding (het)aryl diketones, avoiding tedious chemical protection and deprotection steps. Different alcohol dehydrogenases have been able to selectively reduce the more reactive trifluoroacetyl groups under optimized conditions, while amine transaminases catalyzed the biotransamination of the less hindered acetyl groups. Based on the different reactivity of the acetyl and trifluoroacetyl groups, the design of sequential and concurrent cascades was investigated. The proper selection of the enzymes permits the synthesis of amino alcohol stereoisomers in high to excellent yields (86->99% conversion) and remarkable stereocontrol (up to >99%deand >99%ee) using an aqueous medium and mild reaction conditions.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 521284-22-0. The above is the message from the blog manager. Product Details of 521284-22-0.
Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare