As a common heterocyclic compound, it belongs to chiral-catalyst compound, name is 1,3-Dimesityl-1H-imidazol-3-ium chloride, and cas is 141556-45-8, its synthesis route is as follows.,141556-45-8
SIMes-HCI (100 mg, 0.292 mmol), [Pd(cin)(M-CI)]2 (62.9 mg, 0.122 mmol), a magnetic stir bar and acetone (1.2 mL) were charged into a vial or round bottom flask , followed by K2C03 (33.5 mg, 0.243 mmol). The mixture was stirred at 60 C for 5 h. The general work up procedure was then followed, affording the product as microcrystalline material in 80% (135 mg) yield. XH NMR (400 MHz, CDCh): delta (ppm) =67.12 (m, 3H), 7.06 (m, 2H), 6.96 (d, J = 11.19 Hz, 4H), 5.30 (s, 1 H), 5.12-5.04 (m, 1H), 4.27 (d, J = 12.96 Hz, 1H), 3.99 (m, 4H), 3.27 (d, J = 6.86 Hz, 1H), 2.44 (d, J = 15.24 Hz, 10H), 2.31 (s, 6H), 1.93 (m, 1H). 13C {XH} IMMR (100 MHz, CDCb): delta (ppm) = delta 210.9 (C, carbene), 138.0 (C), 137.8 (C), 136.3 (C), 135.7 (C), 129.1 (CH), 128.0 (CH), 127.5 (CH), 127.1 (CH), 126.4 (CH), 109.4 (CH), 92.1 (CH), 51.0 (CH2), 46.5 (CH2), 20.9 (CHs).Elemental analysis: Expected : C 66.76, H 7.72, N 4.21. Found : C 66.63, H 7.64, N 4.27.
With the complex challenges of chemical substances, we look forward to future research findings about 141556-45-8,belong chiral-catalyst compound
Reference£º
Patent; UMICORE AG & CO. KG; NOLAN, Steven P.; (47 pag.)WO2018/115029; (2018); A1;,
Chiral Catalysts
Chiral catalysts – SlideShare