With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.351498-10-7,6,6′-((1E,1’E)-((2,3-Dimethylbutane-2,3-diyl)bis(azanylylidene))bis(methanylylidene))bis(2,4-di-tert-butylphenol),as a common compound, the synthetic route is as follows.
A 50 mL flask was charged with N,N?-bis(3,5-di-tert-butylsalicylidene)-1,1,2,2-tetramethylethenediamine (0.4302 g, 0.78 mmol, 1.0 equiv), EtOH (17 mL), and Co(OAc)2 (0.1385 g,0.78 mmol, 1.0 equiv). The mixture was degassed and then heated to reflux under nitrogen for 3 h,cooled to room temperature. The precipitate was filtered and the purple solid was washed with EtOH(10 mL) and dried under high vacuum to give 0.3533 g (75%) of the cobalt(II) complex.
As the paragraph descriping shows that 351498-10-7 is playing an increasingly important role.
Reference£º
Article; Zhuang, Linghang; Tice, Colin M.; Xu, Zhenrong; Zhao, Wei; Cacatian, Salvacion; Ye, Yuan-Jie; Singh, Suresh B.; Lindblom, Peter; McKeever, Brian M.; Krosky, Paula M.; Zhao, Yi; Lala, Deepak; Kruk, Barbara A.; Meng, Shi; Howard, Lamont; Johnson, Judith A.; Bukhtiyarov, Yuri; Panemangalore, Reshma; Guo, Joan; Guo, Rong; Himmelsbach, Frank; Hamilton, Bradford; Schuler-Metz, Annette; Schauerte, Heike; Gregg, Richard; McGeehan, Gerard M.; Leftheris, Katerina; Claremon, David A.; Bioorganic and Medicinal Chemistry; vol. 25; 14; (2017); p. 3649 – 3657;,
Chiral Catalysts
Chiral catalysts – SlideShare