With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.602-09-5,[1,1′-Binaphthalene]-2,2′-diol,as a common compound, the synthetic route is as follows.
Add 22.88 g (80 mmol) of binaphthol to 100 mL of acetic acid and 100 mL of CH 2 Cl 2 solution, and add 6.8 mL (160.4 mmol) of fuming HNO3 in an ice bath, and stir at room temperature overnight.TLC detects the formation of new substances and pours the product into ice water for filtration.The solid was washed with CH 2 Cl 2 and methanol.TLC is detected as a point, vacuum dried,The product a6,6′-dinitro(1,1′-binaphthyl-2,2′) diol was obtained., 602-09-5
As the paragraph descriping shows that 602-09-5 is playing an increasingly important role.
Reference£º
Patent; East China Normal University; Liu Qiancai; Ma Junyi; Tao Xuewei; An Shujie; Tang Guofeng; (12 pag.)CN109810124; (2019); A;,
Chiral Catalysts
Chiral catalysts – SlideShare