As a common heterocyclic compound, it belongs to chiral-catalyst compound, name is (R)-2′-amino-[1,1′-binaphthalen]-2-ol, and cas is 137848-28-3, its synthesis route is as follows.,137848-28-3
General procedure: Modified method [67]. 3-tert-Butylsalicylaldehyde (1.78 g,10.0 mmol) was mixed with (R)-2-amino-2′-hydroxy-1,1′-binaphthyl (2.85 g, 10.0 mmol) in dry toluene (50 mL). A few 4 A molecular sieves were added, and the solution was warmed up to 70 Cand kept for two days at this temperature. The solution was filtered and the solvent was removed under reduced pressure. The residue was purified by column chromatography (n-hexane/ethyl acetate= 5:1) to give 2H2 as a yellow solid. Yield: 4.09 g (92%). M.p.: 86-88 C. 1H NMR (C6D6): d 13.28 (s, 1H, OH), 8.31 (s, 1H, CHN), 7.80 (m, 4H, aryl), 7.62 (d, J = 8.4 Hz, 1H, aryl), 7.38 (d, J = 8.9 Hz,1H, aryl), 7.22 (m, 5H, aryl), 7.12 (m, 2H, aryl), 6.87 (d, J = 7.5 Hz,1H, aryl), 6.71 (t, J = 7.6 Hz, 1H, aryl), 4.52 (br s, 1H, OH), 1.45 (s,9H, CH3). These spectroscopic data were in agreement with those reported in the literature [67].
With the complex challenges of chemical substances, we look forward to future research findings about 137848-28-3,belong chiral-catalyst compound
Reference£º
Article; Chen, Liang; Zhao, Ning; Wang, Qiuwen; Hou, Guohua; Song, Haibin; Zi, Guofu; Inorganica Chimica Acta; vol. 402; (2013); p. 140 – 155;,
Chiral Catalysts
Chiral catalysts – SlideShare