Tag: M.W:300-400

14098-24-9, Benzo-18-crown 6-Ether is a chiral-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: The carbonyl substrate (0.1 g) is dissolved in 1-2 mL of anhydrous CHCl3 and 2.0 equiv of a benzocrown ether is added to the solution. To this mixture, CF3SO3H (8.0 equiv; H2SO4 may be used in some cases) is added dropwise with stirring. The reaction is stirred at room temperature for at least 2 h, after which, the mixture is poured over several grams of ice. The resulting solution is extracted three times with CHCl3. The organic phase is subsequently washed three times with water and dried over MgSO4 solution. Removal of the solvent provides the product.

14098-24-9, As the paragraph descriping shows that 14098-24-9 is playing an increasingly important role.

Reference£º
Article; Zielinski, Matthew E.; Tracy, Adam F.; Klumpp, Douglas A.; Tetrahedron Letters; vol. 53; 14; (2012); p. 1701 – 1704;,
Chiral Catalysts
Chiral catalysts – SlideShare

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.141556-45-8,1,3-Dimesityl-1H-imidazol-3-ium chloride,as a common compound, the synthetic route is as follows.

Add ligand L2690mg (2.0mmol), copper powder 640mg (10.0mmol), 30 mL of water in a 50mL flask, 60 ~ 70 oil bath, the reaction was stirred for 24 hours, the reaction mixture was cooled to room temperature, filtered, the filter cake was washed 3 times with water, the filter cake dissolved in acetonitrile and filtered to remove unreacted copper powder, the solvent was evaporated under reduced pressure to give 520mg as colorless crystals, a yield of 65%.

141556-45-8, The synthetic route of 141556-45-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; China Petroleum & Chemical Corporation Shanghai Research Institute of Petrochemical.; Liu, Bo; Jin, Zhaosheng; Lu, Jiangang; Li, Xianming; Zhou, Haichun; (13 pag.)CN105585584; (2016); A;,
Chiral Catalysts
Chiral catalysts – SlideShare

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.141556-45-8,1,3-Dimesityl-1H-imidazol-3-ium chloride,as a common compound, the synthetic route is as follows.

Tris [4- (pyridin-4-yl) phenyl] amine compound (47.6 mg, 0.10 mmol)1,3-bis (2,4,6-trimethylphenyl) imidazole chloride(IMes. HCl) (102.1 mg, 0.30 mmol),PdCl2 (53.2 mg, 0.30 mmol)And potassium carbonate (41.5 mg, 0.30 mmol) were added to a 25 mL single neck flask,Tetrahydrofuran (5 mL) was then added,The reaction was stirred at 75 C for 14 h under argon atmosphere.Stop the reaction,Cool to room temperature,concentrate,Thin layer chromatography to give compound II,Yield 50%., 141556-45-8

As the paragraph descriping shows that 141556-45-8 is playing an increasingly important role.

Reference£º
Patent; Shangqiu Normal University; Wang Tao; Xu Kai; Liu Lantao; Zhao Wenxian; Liu Shuang; Li Feng; Meng Tuanjie; Xie Huanping; (12 pag.)CN105131044; (2017); B;,
Chiral Catalysts
Chiral catalysts – SlideShare

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.173035-10-4,1,3-Dimesityl-4,5-dihydro-1H-imidazol-3-ium chloride,as a common compound, the synthetic route is as follows.

General procedure: [HIPr]2[PdCl4]: 0.45 g (1.0 mmol) of [HIPr]Cl was added to thesolution of 0.14 g (0.48 mmol) PdCl2(cod) in hot CH3CN (5 mL). Themixture was heated for 15 min, until the yellow solution becamered. The solution was cooled to room temperature and solventwas removed under reduced pressure. The product was precip-itated by addition of diethyl ether (2-3 mL). Product yield: 85%;elemental analysis calcd. (%) for PdCl4C54H78N4: C 62.88, H 7.62,N 5.46; found: C 62.37, H 7.46, N 5.40.1H NMR(500 MHz, CD3CN,25C, TMS): = 8.49 (s, 2H, N CH N); 7.57 (t, J(H,H) = 7.8 Hz, 4H,Ar); 7.42 (d, J(H,H) = 7.8 Hz, 8H, Ar); 4.48 (s, 8H, CH2CH2); 3.10(m, J(H,H) = 6.9 Hz, 8H, CH); 1.40 (d, J(H,H) = 6.9 Hz, 24H, CH3); 1.26(d, J(H,H) = 6.9 Hz, 24H, CH3,);13C NMR (125.75 MHz, CD3CN, 25C,TMS): = 160.0 (N CH N); 147.2 (Ar); 131.0 (Ar); 125.5 (Ar); 53.7(CH2CH2); 28.5 (CH); 24.0 (CH3); 23.5 (CH3).

173035-10-4, The synthetic route of 173035-10-4 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Silarska; Trzeciak; Pernak; Skrzypczak; Applied Catalysis A: General; vol. 466; (2013); p. 216 – 223;,
Chiral Catalysts
Chiral catalysts – SlideShare

14098-24-9, Benzo-18-crown 6-Ether is a chiral-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: The carbonyl substrate (0.1 g) is dissolved in 1-2 mL of anhydrous CHCl3 and 2.0 equiv of a benzocrown ether is added to the solution. To this mixture, CF3SO3H (8.0 equiv; H2SO4 may be used in some cases) is added dropwise with stirring. The reaction is stirred at room temperature for at least 2 h, after which, the mixture is poured over several grams of ice. The resulting solution is extracted three times with CHCl3. The organic phase is subsequently washed three times with water and dried over MgSO4 solution. Removal of the solvent provides the product.

14098-24-9, 14098-24-9 Benzo-18-crown 6-Ether 585779, achiral-catalyst compound, is more and more widely used in various fields.

Reference£º
Article; Zielinski, Matthew E.; Tracy, Adam F.; Klumpp, Douglas A.; Tetrahedron Letters; vol. 53; 14; (2012); p. 1701 – 1704;,
Chiral Catalysts
Chiral catalysts – SlideShare

1,3-Dimesityl-4,5-dihydro-1H-imidazol-3-ium chloride, cas is 173035-10-4, it is a common heterocyclic compound, the chiral-catalyst compound, its synthesis route is as follows.,173035-10-4

Synthesis of [(SIMes)CuCl]. This synthesis is as reported in the literature; see S. Diez-Gonzalez et al., J. Org. Chem. 2005, 70, 4784-4796. In a 250 mL Schlenk flask were added copper(I) chloride (1.0 g, 10.10 mmol), 1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydro-imidazol-2-ylidenium chloride (SIMes-HCl, 10.10 mmol), and sodium tert-butoxide (0.97 g, 10.10 mmol). To this flask, dry tetrahydrofuran (100 mL) was added under an inert atmosphere of argon, and the mixture was magnetically stirred for 20 hours at room temperature. After the mixture was filtered through a plug of Celite and then evaporating the solvent under vacuum, a white solid was obtained. 1H NMR (400 MHz, CDCl3) delta=6.96 (s, 4H), 3.96 (s, 4H), 2.32 (s, 12H), 2.30 (s, 6H); 13C NMR (100 MHz, CDCl3) delta=202.8, 138.7, 135.3, 135.0, 129.7, 50.9, 21.0, 18.0. Elemental analysis calcd for C21H26CuClN2: C, 62.21; H, 6.46; N, 6.91. Found: C, 62.60; H, 6.52; N, 6.80%.

As the rapid development of chemical substances, we look forward to future research findings about 173035-10-4

Reference£º
Patent; Institut Catala d’Investigacio Quimica; Institucio Catalana de Recerca i Estudis Avancats; US2009/69569; (2009); A1;,
Chiral Catalysts
Chiral catalysts – SlideShare

173035-10-4, 1,3-Dimesityl-4,5-dihydro-1H-imidazol-3-ium chloride is a chiral-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: An oven-dried Schlenk flask was charged with NHC salt 1 (2.49mmol) and evacuated for 30 min. The flask was then transferredinto a nitrogen-filled glove box and isolated KH (2.49 mmol)was added. The flask was then attached to a Schlenk line(argon/vacuum), evacuated once, and filled with argon. AnhydrousTHF (30 mL) was added, and the slow evolution of hydrogenwas observed. The resulting solution was then allowed tostir for 20 h at r.t. after which time the reaction mixture was filteredthrough a dry filter stick into an oven-dried Schlenk flask.The THF was evaporated, and the resulting free carbene wasextracted into anhydrous toluene (30 mL). The resulting toluenesolution was filtered through another dry filter stick into a previouslyevacuated and oven-dried Schlenk flask containing[(cod)Ir(py)2]PF6 (2, 1.66 mmol). The reaction was allowed tostir for 2 d at r.t. under an argon atmosphere. After this time, themixture was filtered to yield the desired iridium complex 3., 173035-10-4

As the paragraph descriping shows that 173035-10-4 is playing an increasingly important role.

Reference£º
Article; Cross, Paul W. C.; Herbert, John M.; Kerr, William J.; McNeill, Alan H.; Paterson, Laura C.; Synlett; vol. 27; 1; (2016); p. 111 – 115;,
Chiral Catalysts
Chiral catalysts – SlideShare

Benzo-18-crown 6-Ether, cas is 14098-24-9, it is a common heterocyclic compound, the chiral-catalyst compound, its synthesis route is as follows.,14098-24-9

General procedure: The carbonyl substrate (0.1 g) is dissolved in 1-2 mL of anhydrous CHCl3 and 2.0 equiv of a benzocrown ether is added to the solution. To this mixture, CF3SO3H (8.0 equiv; H2SO4 may be used in some cases) is added dropwise with stirring. The reaction is stirred at room temperature for at least 2 h, after which, the mixture is poured over several grams of ice. The resulting solution is extracted three times with CHCl3. The organic phase is subsequently washed three times with water and dried over MgSO4 solution. Removal of the solvent provides the product.

As the rapid development of chemical substances, we look forward to future research findings about 14098-24-9

Reference£º
Article; Zielinski, Matthew E.; Tracy, Adam F.; Klumpp, Douglas A.; Tetrahedron Letters; vol. 53; 14; (2012); p. 1701 – 1704;,
Chiral Catalysts
Chiral catalysts – SlideShare

1,3-Dimesityl-1H-imidazol-3-ium chloride, cas is 141556-45-8, it is a common heterocyclic compound, the chiral-catalyst compound, its synthesis route is as follows.,141556-45-8

V-heterocyclic carbenes were synthesized from their corresponding imidazolium or imidazolinium salts (see Table 1 ). About 0.8 eq. of potassium tert- butoxide (8.9 mg) and 1 eq. of a 1 , 3-disubstituted imidazolium salt (Table 1 , entries 1 – 5) or 1 , 3-disubstituted imidazolinium salt (Table 1 , entry 7) was dissolved in 2 ml_ of tetrahydrofuran (THF). The reaction was stirred for 1 h under argon protection at ambient temperature. The solvent was then removed in vacuo. The resulting carbene was used without further purification and was characterized by 1H NMR and mass spectrometry.

As the rapid development of chemical substances, we look forward to future research findings about 141556-45-8

Reference£º
Patent; SOUTHERN ILLINOIS UNIVERSITY CARBONDALE; WO2008/70756; (2008); A2;,
Chiral Catalysts
Chiral catalysts – SlideShare

1,3-Dimesityl-4,5-dihydro-1H-imidazol-3-ium chloride, cas is 173035-10-4, it is a common heterocyclic compound, the chiral-catalyst compound, its synthesis route is as follows.,173035-10-4

General procedure: An oven-dried Schlenk flask was charged with NHC salt 1 (2.49mmol) and evacuated for 30 min. The flask was then transferredinto a nitrogen-filled glove box and isolated KH (2.49 mmol)was added. The flask was then attached to a Schlenk line(argon/vacuum), evacuated once, and filled with argon. AnhydrousTHF (30 mL) was added, and the slow evolution of hydrogenwas observed. The resulting solution was then allowed tostir for 20 h at r.t. after which time the reaction mixture was filteredthrough a dry filter stick into an oven-dried Schlenk flask.The THF was evaporated, and the resulting free carbene wasextracted into anhydrous toluene (30 mL). The resulting toluenesolution was filtered through another dry filter stick into a previouslyevacuated and oven-dried Schlenk flask containing[(cod)Ir(py)2]PF6 (2, 1.66 mmol). The reaction was allowed tostir for 2 d at r.t. under an argon atmosphere. After this time, themixture was filtered to yield the desired iridium complex 3.

As the rapid development of chemical substances, we look forward to future research findings about 173035-10-4

Reference£º
Article; Cross, Paul W. C.; Herbert, John M.; Kerr, William J.; McNeill, Alan H.; Paterson, Laura C.; Synlett; vol. 27; 1; (2016); p. 111 – 115;,
Chiral Catalysts
Chiral catalysts – SlideShare