One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 80657-57-4, Name is (S)-Methyl 3-hydroxy-2-methylpropanoate, formurla is C5H10O3. In a document, author is Dong, Chao, introducing its new discovery. Product Details of 80657-57-4.
An enantioselective Rh-catalyzed hydrogenation of E/Z mixtures of trisubstituted vinyl esters has been disclosed. With a combination of [Rh(COD)(2)]BF4 and a structurally fine-tuning chiral ferrocenylphosphine-phosphoramidite ligand as the catalyst, a variety of E/Z mixtures of alpha-aryl-beta-alkylvinyl esters have been successfully hydrogenated in high yields and with good to high enantioselectivities (up to 96% ee). The presence of a small amount of (BuOH)-Bu-t proved to be beneficial to improve the hydrogenation outcome. (C) 2021 Elsevier Ltd. All rights reserved.
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Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare