Name is trans-Cyclohexane-1,2-diamine, as a common heterocyclic compound, it belongs to chiral-catalyst compound, and cas is 1121-22-8, its synthesis route is as follows.,1121-22-8
It was prepared according to the method reported by Elshaarawy et al. [23] with slight modifications, in brief, at 70C, rac-trans-1,2-diaminocyclohexane (6mL, 50.0mmol) was added dropwise to a solution of l-(+)-tartaric acid (7.5g, 50.0mmol) in distilled water (20mL). Then the reaction temperature was gradually increased until 90C in order to keep the mixture solubilized. The resulting slurry was stirred at the same temperature for a further 2h, and then the isotropic solution was allowed to spontaneously cool down to RT and then kept at 4C overnight. The resulting precipitate was collected by vacuum filtration and washed with 5C distilled water (2¡Á25mL) and then methanol (5¡Á15mL). The crude product, 3, was then recrystallized by dissolving the compound in distilled water at 90C and leaving to cool to RT overnight. The recrystallization process was repeated twice. The purified product was collected by vacuum filtration and dried under reduced pressure. 1H NMR (200MHz, D2O) delta (ppm): 4.64 (d, J=7.1Hz, 2H), 4.15 (td, J=10.8, 3.9Hz, 1H), 3.98 (td, J=10.6, 4.1Hz, 1H), 2.71 (3, 6H), 2.38-2.13 (m, 4H), 1.67-1.89 (m, 4H).
With the complex challenges of chemical substances, we look forward to future research findings about trans-Cyclohexane-1,2-diamine
Reference£º
Article; Elshaarawy, Reda F.M.; Ali, Reham; Saleh, Sayed M.; Janiak, Christoph; Journal of Molecular Liquids; vol. 241; (2017); p. 308 – 315;,
Chiral Catalysts
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