The important role of 23190-16-1

With the complex challenges of chemical substances, we look forward to future research findings about (1R,2S)-2-Amino-1,2-diphenylethanol

Name is (1R,2S)-2-Amino-1,2-diphenylethanol, as a common heterocyclic compound, it belongs to chiral-catalyst compound, and cas is 23190-16-1, its synthesis route is as follows.,23190-16-1

Step 1 : A mixture of (li?,25)-2-amino-1,2-diphenylethanol (4.28 g, 20.0 mmol), K2CO3 (0.28 g 2.03 mmol) and diethyl carbonate (20 mL, 166 mmol) was heated under reflux for 16 h. The resulting mixture was washed with water (10 mL) and extracted with CH2Cl2 (300 mL). The organic phase was dried MgSO4, filtered and concentrated. The residue was recrystallized form toluene to give the desired compound (4S,5i?)-4,5-diphenyloxazolidin-2-one as white solid. Yield 88%, ESI-MS: 240.1 [M+]

With the complex challenges of chemical substances, we look forward to future research findings about (1R,2S)-2-Amino-1,2-diphenylethanol

Reference£º
Patent; ACHAOGEN, INC.; WO2009/55696; (2009); A1;,
Chiral Catalysts
Chiral catalysts – SlideShare