72657-23-9, Name is (R)-Methyl 3-hydroxy-2-methylpropanoate, molecular formula is C5H10O3, belongs to chiral-catalyst compound, is a common compound. In a patnet, author is Pototskiy, Roman A., once mentioned the new application about 72657-23-9, HPLC of Formula: C5H10O3.
A new chiral cyclopentadiene (CpH)-H-myr was synthesized from the natural terpene (R)-myrtenal in 5 steps and about 40 % total yield. The key step was the reaction of vinyl-dibromocyclopropane derivative with MeLi which provided the diene (CpH)-H-myr via Skattebol rearrangement. The reaction of (CpH)-H-myr with [(cod)Rh(OAc)](2)gave the rhodium(I) complex (Cp-myr)Rh(cod) and subsequent oxidation with halogens X(2)gave the rhodium(III) complexes [(Cp-myr)RhX2](2)(X = Br, I). Complex (Cp-myr)Rh(cod) in combination with benzoyl peroxide catalyzed the C-H activation ofO-pivaloyl-phenylhydroxamic acid and its subsequent annulation with alkenes giving dihydroisoquinolones with high yield (70-90 %) but moderate enantioselectivity (16-36 %ee).
If you¡¯re interested in learning more about 72657-23-9. The above is the message from the blog manager. HPLC of Formula: C5H10O3.
Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare