Chemistry, like all the natural sciences, Recommanded Product: (S)-1-Aminopropan-2-ol, begins with the direct observation of nature¡ª in this case, of matter.2799-17-9, Name is (S)-1-Aminopropan-2-ol, SMILES is C[C@H](O)CN, belongs to chiral-catalyst compound. In a document, author is Meyer, Stephanie, introduce the new discover.
An I(I)/(III) catalysis strategy to construct an enantioenriched fluorinated isostere of the Pr-i group is reported. The difluorination of readily accessible alpha-CF3-styrenes is enabled by the in situ generation of a chiral ArIF2 species to forge a stereocentre with the substituents F, CH2F and CF3 (up to 95 %, >20:1 vicinal:geminal difluorination). The replacement of the metabolically labile benzylic proton results in a highly preorganised scaffold as was determined by X-ray crystallography (pi ->sigma* and stereoelectronic gauche sigma ->sigma* interactions). A process of catalyst editing is disclosed in which preliminary validation of enantioselectivity is placed on a structural foundation.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 2799-17-9. Recommanded Product: (S)-1-Aminopropan-2-ol.
Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare