Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 521284-22-0, Name is (R)-2-((4-Aminophenethyl)amino)-1-phenylethanol hydrochloride, molecular formula is C16H21ClN2O, belongs to chiral-catalyst compound, is a common compound. In a patnet, author is Wheatley, Emilie, once mentioned the new application about 521284-22-0, SDS of cas: 521284-22-0.
A general method for the synthesis of secondary homoallylic alcohols containing alpha-quaternary carbon stereogenic centers in high diastereo- and enantioselectivity (up to >20:1 dr and >99:1 er) is disclosed. Transformations employ readily accessible aldehydes, allylic diboronates, and a chiral copper catalyst and proceed by gamma-addition of in situ generated enantioenriched boron-stabilized allylic copper nucleo-philes. The catalytic protocol is general for a wide variety of aldehydes as well as a variety of 1,1-allylic diboronic esters. Hammett studies disclose that diastereoselectivity of the reaction is correlated to the electronic nature of the aldehyde, with dr increasing as aldehydes become more electron poor.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 521284-22-0. The above is the message from the blog manager. SDS of cas: 521284-22-0.
Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare